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Vancouver, ON, — Canada’s first drug manufacturer to make a new version of a prescription drug for erectile dysfunction (ED) without a prescription, will begin distributing its new drug, Viagra Connect, on Friday.

The first product from its Canadian subsidiary, Biotest, will come as the company makes the first oral ED drug,, which is not in the same class as Viagra.

“For men looking for a reliable solution for ED, we’ve developed a new drug that’s proven to be very effective,” said David Krennan, Biotest’s chief executive officer.

Biotest has a team of 20 medical professionals who have been working on the drug since it was first approved in the United States in 2003. The company has received FDA approval in Canada for a generic version, Cialis, but also has received approval for the original version in Europe.

The new product, called sildenafil, works by increasing blood flow to the penis, and it was designed to be taken orally and is not available over the counter.

The new drug will cost about $30 for a one-month supply, which makes it a more affordable option than the older version, Cialis, which has more to offer men.

In the United States, sildenafil is approved for men 18 and older who have erectile dysfunction and are seeking treatment. Viagra Connect will be available in pharmacies in all 50 states.

Biotest will be distributed in four cities across the country — the Vancouver, British Columbia, Edmonton, and Calgary — and will be available for free online at its website,.

Biotest Inc. — Canadian Pharmacy Division

Biotest’s CEO, Dave Krennan, said that while the company was pleased with the new product, he wasn’t sure that the new drug was effective enough for men looking to buy it.

“It’s definitely not going to work for everyone. We’ve been testing the drug for over 20 years and there was no real difference in effectiveness,” said Krennan, adding, “The first product we’ll ever get approved for is sildenafil but we’ll see who can get it.”

Biotest also said that men in the United States, including those seeking treatment for ED, shouldn’t use the drug to obtain medical treatment. Viagra Connect is not a medication for those who are trying to treat a specific disease or condition, Krennan said.

“For men looking to get the best results with ED, Viagra Connect is a great option,” Krennan said. “This is a brand-name drug and we’re excited to begin distributing it to men in Canada.”

Cialis, which was designed to be taken orally, is a prescription-only drug that is not available over the counter in Canada. According to the Canadian Food Drug Association (CFFDA), men with erectile dysfunction (ED) can get the drug without a prescription in Canada.

Cialis is the first FDA-approved drug for the treatment of erectile dysfunction, which is the most common type of male sexual disorder. The drug is designed to treat symptoms such as an erection, difficulty getting or keeping an erection, and decreased sexual desire.

Biotest is based in the U. S., and the company is currently working on a second product to make its drug available in Canada.

Cialis has been shown to cause some mild side effects. Talk to your health care provider if these do not go away within a few days. If you begin to experience more serious reactions, seek medical attention immediately.

Common side effects reported from Cialis use include:

  • Headache
  • Indigestion
  • Heartburn
  • Upset stomach
  • Gas
  • Nausea
  • Flushing

More severe side effects include:

  • Painful erections or erections that last longer than 4 hours
  • Sudden loss of vision
  • Sudden loss of hearing
  • Ringing in the ears
  • Chest pain
  • Shortness of breath
  • Painful urination
  • Increased urination frequency
  • Fainting
  • Dizziness
  • Skin rash
  • Hives
  • Facial swelling

If you experience any of these side effects, seek medical attention immediately. These are symptoms of a severe adverse reaction to this medication that require immediate treatment.

As with all prescription medications, inform your doctor of any medical conditions you currently manage. Tell them about any and all medications, prescription drugs, and supplements you are taking before starting treatment with Cialis. Cialis can interact with bodily substances, causing potentially serious adverse reactions.

Specifically, you should inform your health care provider of any alpha-blocker, antifungal, HIV protease inhibitor, or high blood pressure medication you are taking. Remember to mention any herbal products you use, especially St. John’s wort.

In addition, let your doctor know if you have recently had heart surgery or experience chest pain during sex. If you experience any changes in your heartbeat or chest pain during sex, contact your health care provider immediately.

Read More What is Cialis and how it works 'Cialis' is a prescription medication that contains the active ingredient tadalafil. 'Cialis' is a prescription medication that contains the active ingredient tadalafil. 'Cialis' is a type of medication called a phosphodiesterase type 5 (PDE5) inhibitor. PDE5 enzymes are made necessary to pump blood around in the penis. By blocking the action of PDE5, Cialis helps to widen the blood vessels, allowing more blood to flow into the penis. This allows for an erection to be made during sex.'Cialis' is a type of medication called a phosphodiesterase (PDE)5 inhibitor.

As with all prescription medications, inform your doctor if you are unable to get an erection or if you experience any uncomfortable side effects.

What is the difference between Cialis (generic Viagra) and generic Viagra (Cialis). How Cialis (Tadalafil) and generic Viagra (Cialis) compare. 'Cialis' is a generic version of Viagra, while 'Viagra' is a brand-name formulation of the drug. 'Cialis' can be taken with or without food, but it is recommended to take it at a fixed time to help maintain a constant level of the drug in the body. 'Tadalafil' is an oral formulation of Sildenafil (generic Cialis) that is available in various forms, including generic and brand-name. 'Tadalafil' can be taken just before, during, or up to a certain recommended dose of Sildenafil.

Cialis can be taken before or after a meal to prevent lightheadedness. However, it is recommended to take Cialis at the same time to ensure its effectiveness. Cialis can be taken advantage of without having to worry about timing or side effects.

If you have any changes to make, you should know about them before using Cialis. Your doctor mayaSTON!

Source: PharmacyDaily.

Interactions

A. Top Drug-Drug Interactions:

1.Nitrates (e.g., nitroglycerin, isosorbide dinitrate): Cialis and nitrates both lower blood pressure. Taking them together can cause a significant and potentially life-threatening drop in blood pressure (hypotension), leading to dizziness, fainting, or even heart attack or stroke. It is contraindicated to use Cialis with nitrates or recreational "poppers" (amyl nitrites).

2.Alpha-blockers (e.g., prazosin, terazosin, tamsulosin): Both Cialis and alpha-blockers relax blood vessels, which can lead to excessive blood pressure reduction when used together. This may result in dizziness, fainting, or orthostatic hypotension (a sudden drop in blood pressure when standing). If needed, your doctor may adjust the dosage or recommend spacing the medications.

3.Other antihypertensive drugs (e.g., atenolol, propranolol, enalapril, lisinopril): Cialis can enhance the blood-pressure-lowering effects of these medications. While this interaction is usually less severe than with nitrates or alpha-blockers, it can still cause dizziness or fainting in sensitive individuals. Close monitoring of blood pressure is recommended.

Other Drug-Drug interactions:

  • Ketoconazole, itraconazole (used to manage fungal infection)
  • Protease inhibitors (used to manage HIV infection) Ex. ritonavir, lopinavir
  • Phenobarbital, phenytoin, carbamazepine (medicines used for fits)
  • Rifampicin, erythromycin, clarithromycin (medicines used for bacterial infections)
  • Other medicines used to improve blood flow to the penis (Ex. sildenafil)

B. Drug-Food Interactions:

Cialis (tadalafil) can interact with certain foods and beverages, potentially altering its effectiveness or increasing the risk of side effects. Here are the key drug-food interactions to be aware of:

  1. Grapefruit and Grapefruit Juice: Grapefruit can increase the levels of tadalafil in your blood by interfering with its metabolism. This may amplify side effects, such as headaches, dizziness, or low blood pressure. Avoid consuming grapefruit or grapefruit juice while taking Cialis.
  2. Alcohol: Drinking alcohol with Cialis can enhance the blood pressure-lowering effects of the medication, leading to symptoms like dizziness, lightheadedness, or fainting. Limiting alcohol intake is recommended while using Cialis.
  3. High-Fat Meals: While Cialis can be taken with or without food, consuming it with a high-fat meal may delay its onset of action. Opt for lighter meals if rapid effectiveness is needed.
  4. Caffeine: Though not a direct interaction, combining Cialis with high caffeine intake might worsen side effects like headaches or increase heart rate in sensitive individuals.
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Tadalafil,, and, also have can interact with certain foods and beverages, potentially altering their effectiveness or increasing the risk of side effects. Here are the key drug-food interactions:

  1. GrapefruitThis can amplify side effects like dizziness or fainting.
  2. : Though not a direct interaction, combining Cialis with grapefruit might make them more likely to interact. Your doctor will determine whether the medication is appropriate during your treatment.
  3. : While While These may be suitable for individuals who are sensitive to can increase the blood pressure-lowering effects of tadalafil, it is not advised to consume grapefruit or other foods with.

Cialis has been shown to cause some mild side effects. Talk to your health care provider if these do not go away within a few days. If you begin to experience more serious reactions, seek medical attention immediately.

Common side effects reported from Cialis use include:

  • Headache
  • Indigestion
  • Heartburn
  • Upset stomach
  • Gas
  • Nausea
  • Flushing

More severe side effects include:

  • Painful erections or erections that last longer than 4 hours
  • Sudden loss of vision
  • Sudden loss of hearing
  • Ringing in the ears
  • Chest pain
  • Shortness of breath
  • Painful urination
  • Increased urination frequency
  • Fainting
  • Dizziness
  • Skin rash
  • Hives
  • Facial swelling

If you experience any of these side effects, seek medical attention immediately. These are symptoms of a severe adverse reaction to this medication that require immediate treatment.

As with all prescription medications, inform your doctor of any medical conditions you currently manage. Tell them about any and all medications, prescription drugs, and supplements you are taking before starting treatment with Cialis. Cialis can interact with bodily substances, causing potentially serious adverse reactions.

Specifically, you should inform your health care provider of any alpha-blocker, antifungal, HIV protease inhibitor, or high blood pressure medication you are taking. Remember to mention any herbal products you use, especially St. John’s wort.

In addition, let your doctor know if you have recently had heart surgery or experience chest pain during sex. If you experience any changes in your heartbeat or chest pain during sex, contact your health care provider immediately.

Tell your doctor if you are pregnant or breastfeeding, or if you have any kidney or heart problems.If you have, or have ever had, a heart attack, stroke, vision loss, heart failure, or heart pains in the past 12 hours, asks about the effects of Cialis. Cialis can interact with drugs used to treat heart problems, such as nitrates.Given the severity of the infection, Cialis can cause potentially serious effects.

As with all prescription medications, inform your doctor of any medical conditions you used to get treatment for such as diabetes, migraine, and mental health conditions.

As with all prescription medications, inform your doctor if you're having a heart-related problem or if you have ever had an heart attack or stroke. Cialis can interact with medications such as nitrates and drugs used to treat heart problems, such as nitroglycerin.

As with all prescription medications, inform your doctor if you have, or have ever had, liver or kidney problems. Cialis can cause potentially serious effects in the liver, especially if you are taking medications that affect liver enzymes.

As with all prescription medications, inform your doctor if you are pregnant, plan to become pregnant, or are breastfeeding.

As with all prescription medications, inform your doctor if you have, or have ever had, a, or if you are planning, if you areodle, if you use condoms, if you have ever had an erection that lasted more than 4 hours, or if you are pregnant.

As with all prescription medications, be sure to speak to your doctor before starting Cialis, as the virus that causes Cialis makes it very difficult to get pregnant.

As with all prescription medications, be sure to speak to your doctor before starting Cialis, as the virus that causes Cialis makes it extremely difficult to get pregnant.